Is it better to take micardis or micardis HCT?

The only difference between Micardis and Micardis HCT is that the latter is a combination drug, comtaining both Micardis and Hydrochlorothiazide (otherwise known as HCT or HCTZ). HCT is a diuretic.

The only reason you would need to take Micardis HCT would be if you are already taking HCTZ, and it just cuts taking two pills down into one.

Could the medication Topamax be enough to treat bipolar disorder by itself?

In fact, an individual with bipolar disorder who is on the verge of a manic episode can be "bumped-up" into full-blown mania if an antidepressant is taken. Topamax being "enough" to treat bipolar disorder, in addition to it being traditionally used as an anti-seizure med it also has mood-stabilizing properties, as do many of the anticonvulsants (benzodiazepines excluded, as they work based on a different mechanism). The reason for this (and here's where I turn into a really big nerd) is that we are finally beginning to realize that the neurotransmitters have more than one function. For example, one neurotransmitter may play a role in mood, pain sensation, as well as proper electrical activity of the brain and muscles, so it follows that a medication that may be used to slow the electical impulses of the brain (and thus the signals to the rest of the body) as in the case of anti-epileptics may have the secondary effect of controlling mood, or at least making it more stable. (Another good example of this is the use of Neurontin or Lyrica to treat nerve pain associated with chonic pain or acute pain post-operatively.)